Newer Therapeutics for Patients with Inhibitors
نویسندگان
چکیده
disorder due to deficiency of factor VIII and IX respectively. However, 1/3rd cases are due to spontaneous mutations. These patients present with bleeding. The platelet count, BT and PT are normal but APPT is deranged. Correction of APTT on mixing with normal plasma suggests intrinsic pathway defect. Normal factor levels are between 50% -150%. Hemophilia is defined as mild (factor levels >5% to 40%), moderate (1-5%) and severe (<1%).
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تاریخ انتشار 2017